Mean Girls is a musical adaptation of the 2004 film, following Cady Heron, a teenager moving from homeschooling in Africa to a suburban Illinois high school. She navigates a treacherous social hierarchy, befriending outsiders Janis and Damian, who encourage her to infiltrate and destroy "The Plastics," a popular clique led by ruthless Queen Bee Regina George. Cady becomes a "Plastic" herself but loses her true self in the process, leading to a showdown of revenge, social ruin, and eventual redemption.